Guidelines for the use of drugs in the field of Internal Medicine with its 12 Sub-Specialists are absolutely necessary because the types of drugs in circulation are very diverse. The PB PAPDI Formulary Compilation Team in preparing the drugs to be used refers to: Management of various diseases in the Handbook of Internal Medicine, the Handbook of Medical Services in Internal Medicine and existing consensus or adopted by the Subspecialist Association which is certainly arranged based on the principles of efficiency, safety, quality, availability and economical prices.