The complexity of diseases and drug use, as well as highly individualized patient responses, increase the occurrence of drug-related problems. One of the pharmaceutical services that must be performed in order to deal with drug-related problems is Drug Therapy Monitoring (PTO). The PTO process includes assessment of drug choice, dose, mode of administration, therapeutic response, adverse drug reactions (ROTDs), and recommendations for changes or alternatives to therapy. )dan rekomendasi perubahan atau alternatif terapi.